Fig. 3

Endometrial hyperplasia. Panel A: simple (glandulo-cystic) hyperplasia is characterized by a heterogeneous growth of the mucosa. The glands are irregularly developed, some being dilated, cystic, and others atrophic. Panel B illustrates a complex hyperplasia of the endometrium, with formation of morules inside the lumen of branching glands. Endometrial intra-epithelial neoplasia developed in this case of complex hyperplasia, as assessed by an exaggerated glandular crowding, loss of nuclear polarity and mild cellular atypias