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Table 3 A summary of randomized controlled trials of the use of misoprostol ripening of the cervix before hysteroscopy

From: A prospective, randomized, controlled trial comparing vaginal misoprostol and osmotic dilator in achieving cervical ripening before operative hysteroscopy

 Reference Misoprostol Spontaneous dilator (mean±SD, mm) Comparison group Spontaneous dilator (mean±SD, mm)
[10] 200 μg, 9–10 h, vaginally, n=46 7.0±1.0 Placebo n=45 3.8±1.2
[11] 200 μg, 9–10 h, vaginally, n=73 7.3±0.7 Placebo n=79 3.8±1.1
[15]a 200 μg, 8 h, vaginally, n=72 7.5±1.2 Laminaria 8 h, n=72 7.6±1.2
[12] 400 μg, 12 h, vaginally, n=51 7.6±1.4 No agent n=54 5.0±1.1
Current study 400 μg, 12 h, vaginally, n=53 8.0±1.8 The synthetic osmotic dilator 12 h, n=47 9.6±2.2
  1. aA comparison of Laminaria vs. misoprostol