From: Isolated Langerhans cell histiocytosis of the vulva: a case report and review of the literature
Report | Age | Clinical presentation | Excision | Radio-therapy | Chemotherapy | Others | Response | Outcome (months) |
---|---|---|---|---|---|---|---|---|
Weidmann [9] | Unknown | Ulcers | + | − | − | − | PR | LTF |
Rose [10] | 50 | Ulcers | − | + | − | − | PR | LTF |
Axiotis et al. [7] | 85 | Ulcers | − | − | − | Corticosteroid | No response | LTF |
Voelklein et al. [11] | 36 | Ulcers | − | + | − | − | CR | NEOD (12) |
Savell et al. [12] | 76 | Erythematous plaques | − | − | + | − | CR | NEOD (8) |
Solano et al. [13] | 40 | Erythematous plaques | + | − | + | − | CR | NEOD (18) |
Pather et al. [14] | Unknown | Ulcers | + | − | − | − | CR | NEOD (24) |
Santillan et al. [15] | 33 | Nodular lesion | + | + | − | Thalidomide | CR | NEOD (5) |
Dietrich et al. [16] | 41 | Nodular lesion | + | + | + | − | CR | LTF |
29 | Nodular lesion | + | + | − | Corticosteroid | PR | LTF | |
Padula et al. [8] | 31 | Ulcers | + | + | − | Thalidomide | CR | NEOD (36) |
52 | Ulcers | − | + | − | − | CR | NEOD | |
Venizelos et al. [17] | 64 | Ulcers | + | + | − | − | CR | NEOD (22) |
Ishigaki et al. [18] | 65 | Ulcers | + | − | − | − | CR | NEOD (12) |
Mlyncek et al. [4] | 63 | Ulcus | + | − | − | − | CR | NEOD (12) |
Present report | 49 | Nodular lesion and ulcers | + | + | − | − | CR | NEOD (41) |