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Table 1 Serum bupivacaine levels, pain score and postoperative analgesia in study participants

From: Transcervical intrauterine bupivacaine for the management of postoperative pain following endometrial balloon ablation—a pre-trial toxicity study

Participant number (study group) Serum bupivacaine (3 h postoperative; mg/L) Pain scores at recovery/dischargea Diclofenac Paracetamol Other analgesia Morphine (total dose)
1 <0.1 0/1 100 mg PR 1 g PR Codeine 60 mg
2b 0.1 3/0 100 mg PR 1 g iv Codeine 60 mg 10 mg
3 Wrong sample 0/0 100 mg PR 1 g PR
4b 0.5 2/0 50 mg iv 1 g Buscopan 10 mg 10 mg
5 <0.1 1/1 Codeine 60 mg
6 0.1 1/1 75 mg iv 1 g PR
7 1.3 1/1 50 mg iv 1 g iv
8 <0.1 2/1 100 mg PR 1 g PR Codeine 60 mg
1 g iv
9 <0.1 0/1 75 mg iv 1 g PR Co-codamol × 2
10 0.5 1/1 75 mg iv 1 g PR Codeine phos 60 mg
  1. aPain score—verbal scale of 0–4 (standard use in recovery—East Lancashire Hospital NHS Trust; 0—none, 1—mild pain, 2—mild but moderate on movement, 3—moderate but severe on movement and 4—severe at rest)
  2. bRequired overnight stay