Table 1 Sixteen cases of primary uterine angiosarcoma diagnosed by morphology and immunohistochemistry
Year | Age | Macroscopic features | Surgery | Adjuvant chemotherapy | Adjuvant irradiation | PFS months | OS months | Metastasis |
|---|---|---|---|---|---|---|---|---|
1987 | 71 | Massive enlargement of uterus | TAH, BSO | None | Yes | 3 | 3 | NA |
1990 | 76 | Massive enlargement of uterus | TAH, BSO | None | None | 6 | 6 | NA |
1991 | 65 | 4.7-cm hemorr mass + bulky uterus | TAH, BSO LN | Cisplatin + adriamycin | Yes | 47 | 47 | NA |
1993 | 56 | Multiple hemorr myoma | TAH, BSO LN | Ifosfamide + adriamycin | Yes | 2 | 7 | NA |
1993 | 61 | 10-cm uterine mass | TAH, BSO | None | None | 1 | 1 | NA |
1994 | 58 | 12-cm mass | TAH, BSO | Unspecified type | Yes | 2 | 2 | NA |
1998 | 49 | 6.3-kg uterine mass | TAH, BSO | None | None | 3 | 3 | NA |
58 | 12-cm uterine mass | TAH, BSO | Unspecified type | Yes | 2 | 2 | NA | |
70 | 5-cm polypoid lesion, half myoma | TAH, BSO | None | None | 36 | 36 | NA | |
75 | 6.3-cm lower uterus | TAH, BSO | None | None | 7 | 7 | NA | |
1999 | 59 | 12-week size uterus | TAH, BSO LN | None | None | 0.4 | 2.5 | Vaginal, lung, brain |
2001 | 67 | 25x21-cm uterus | TAH, BSO | None | None | 0 | 15 | Gingival, lung, brain |
2008 | 81 | 200-g uterus | TAH, BSO | None | None | 0 | 6 | Peritoneal spread |
35 | 2.400-g uterus | TAH, BSO | NA | NA | 0 | NA | Peritoneal + pleural spread | |
2008 | 54 | 11-cm bulky uterus | TAH, BSO | Gemcitabine + taxotere | None | 3 | 12 | Peritoneal + pleural spread |
Bevacizumab | ||||||||
2009 | 58 | 2.500-g uterus | TAH, BSO | Ifosfamide + adriamycin | None | 3 | 53 | Bone, lung, gingival, heart |