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Fig. 2 | Gynecological Surgery

Fig. 2

From: HMG-CoA reductase inhibitor lovastatin upregulates plasminogen activator production through RhoA-signaling in peritoneal cell line Met5A

Fig. 2

Tissue-type plasminogen activator (tPA) protein level in Met5A cells exposed to geranylgeranyl pyrophosphate (GGPP) or C3 transferase. Met5A cells were exposed to lovastatin (1 µM), lovastatin and GGPP (1 µM), C3 (1 µg/ml), or lovastatin, GGPP, and C3 for 18 h. tPA protein content of cell lysate was measured by tPA enzyme-linked immunosorbent assay kit. Values are expressed as means optical density (450 nm) ± SD of three independent experiments performed in duplicate determination. *P < 0.05 versus control

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