Fig. 4From: HMG-CoA reductase inhibitor lovastatin upregulates plasminogen activator production through RhoA-signaling in peritoneal cell line Met5ARhoA activity in Met5A cells exposed to lovastatin. Met5A cells were exposed to lovastatin (1 µM), lovastatin and geranylgeranyl pyrophosphate (GGPP; 1 µM), C3 (1 µg/ml), or lovastatin, GGPP, and C3 for 18 h. Values are expressed as means optical density (490 nm) ± SD of three independent experiments performed in duplicate determination. *P < 0.05 versus controlBack to article page