Total laparoscopic hysterectomy versus total abdominal hysterectomy with bilateral salpingo-oophorectomy for endometrial carcinoma: a randomised controlled trial with 5-year follow-up

Table 2 Data on surgical procedures and oncological outcome by treatment group

	LH (n = 11)	AH (n = 6)	P value
Intra-operative laparoconversion	1 (9%)	n.a.	n.a.
Operation time (min)	122 [96–168]	80 [70–192]	0.03
Blood loss (mL)	200 [0–550]	350 [300–1450]	0.01
Hospitalization (days)	5 [4–16]	8 [5–11]	0.03
Clinical follow-up (months)	54 [18–80]	64 [50–81]	0.09
Diseased after recurrence	2 (18%)	0	0.40
Postoperative histology
Normal	1 (9%)	0
Atypical hyperplasia	0	1 (17%)
Endometrial carcinoma^a	10 (91%)	5 (83%)	0.60
Postoperative radiotherapy	3 (27%)	3 (50%)	0.34

Data shown as absolute numbers (percentage) or median [range]. p = p value for differences between groups using Fisher's exact test in cases of 2-by-2 tables, and Mann–Whitney test in cases of non-normal distributed numerical variables
AH abdominal hysterectomy, LH laparoscopic hysterectomy, n.a. not applicable
^aEndometrial carcinomas were stage 1b grade 1 (2 patients), 1c grade 1, 2a grade 1, and 3a grade 1 in the AH group, and 1a grade 1, 1b grade 1 (3 patients), 1b grade 2, 1c grade 1, 1c grade 2 (2 patients), 2b grade 1 and 3a grade 2 in the LH group. All histologies showed endometroid type adenocarcinoma, except one woman in the LH group with stage 3a grade 2 mixed cell-type tumour (endometroid and serous adenocarcinoma)