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Table 4 Estimated increase in questionnaire score level (95%confidence interval) by treatment group, by unit increase in baseline score and point of measurement using a linear mixed model

From: Total laparoscopic hysterectomy versus total abdominal hysterectomy with bilateral salpingo-oophorectomy for endometrial carcinoma: a randomised controlled trial with 5-year follow-up

 

RAND-36

QoR-40

RI-10

Treatment groupa

 LH

142 (46; 236)

9 (−3; 21)

7 (0; 14)

 AH

0 (reference)

0 (reference)

0 (reference)

Baseline effect

 per 10 unitsb

7 (4; 11)

5 (1; 9)

n.a.

Time after surgery

 1 day

n.a.

0 (reference)

n.a.

 2 days

n.a.

4 (−3; 12)

n.a.

 3 days

n.a.

4 (−4; 11)

n.a.

 1 week

0 (reference)

13 (6; 20)

0 (reference)

 2 weeks

−8 (−64; 47)

26 (18; 33)

0 (−3; 2)

 4 weeks

49 (−6; 105)

n.a.

4 (1; 6)

 6 weeks

130 (74; 185)

n.a.

6 (4; 9)

 12 weeks

122 (67; 178)

n.a.

8 (5; 11)

  1. Example: On average, the estimated level of the total RAND-36 score in the LH group was 142 units higher as compared with the AH group, at each timepoint from 2 to 12 weeks after surgery. The estimated increase per 10 units higher level in the total RAND-36 score at baseline between two patients was 7 units. This was independent of both timepoint and treatment group. Furthermore, the estimated increase in the total RAND-36 score at 12 weeks after surgery, compared to 1 week after surgery, was 122 units in both groups
  2. Because the data fit very well to the parallel-line model the differences over time after surgery is estimated to be identical in both groups (see also Fig. 2a, b and c)
  3. LH laparoscopic hysterectomy, AH abdominal hysterectomy, RAND-36 RAND 36-Item Short Form Health Survey, QoR-40 Quality of Recovery-40, RI-10 Recovery Index-10, n.a. not applicable
  4. aDifference between groups after correction for baseline differences
  5. bThe baseline effect is the increase in postoperative score per 10 units increase at baseline