Skip to main content

Table 1 Summary of studies regarding endometrial cancer investigations and hysteroscopy

From: Indications of diagnostic hysteroscopy, a brief review of the literature

Hysteroscopy in endometrial cancer

Summary of publication—Findings.

Year of study

Number of women

Type of publication

Tanizawa O et al.

No significant differences in the presence of intraperitoneal tumor cells.

1991

1,040

Observational

Taddei GL et al.

Hysteroscopic evaluation of endometrial cavity and cervical canal in women with endometrial adenocarcinoma has beneficial effects on woman's survival rates.

1994

235

Observational

Fay TN et al.

Hysteroscopic assessment of endometrial cavity efficient in the detection of pathological intrauterine lesions but only moderately successful determining physiological endometrial changes.

1999

83

Multicenter randomized double-blind control trial.

Nagele F et al.

No significant difference in the spreading of endometrial malignant cells either by CO2 or N/S as a distention media for hysteroscopy.

1999

30

Prospective randomized self-controlled study

Clark TJ et al.

The diagnostic accuracy of hysteroscopy is high for endometrial cancer and moderate for endometrial disease.

2002

26,346

Systemic quantitative review

Revel A et al.

An increased risk of peritoneal contamination of malignant cells after hysteroscopy but with no evidence for the patients to face worsen prognosis.

2004

 

Systemic review

Takac I et al.

Diagnostic hysteroscopy significantly increases the risk of positive peritoneal cytology but not the risk of adnexal, abdominal or retroperitoneal lymph node metastases in women with endometrial cancer.

2007

146

Retrospective randomized trial

De Sousa Damiao et al.

If hysteroscopy is performed under a low pressure of CO2, no spread of endometrial cells occur into the peritoneal cavity.

2009

76

Prospective longitudinal study

Polyzos NP et al.

Hysteroscopy resulted in a significantly higher rate of malignant peritoneal cytology especially if the distention medium was N/S and the inflated media pressure exceeded 100 mmHg.

2010

1,015

Systematic review and meta-analysis