Cross-linked xenogenic collagen implantation in the sheep model for vaginal surgery

Table 1 Paired comparison of outcomes of vaginally and abdominally implanted ACMs

	ACM		Paired comparison
	Abdomen	Posterior vagina	Paired comparison
Graft-related complication	3/10 (30 %)	5/10 (50 %)	ns
Exposure	0/10 (0 %)	1/10 (10 %)
Folding	0/10 (0 %)	2/10 (20 %)
Induration	3/10 (30 %)	2/10 (20 %)
Other gross anatomical findings
Thickness (mm)	8.22 ± 3.90	6.78 ± 2.27	ns
Material not identifiable	0/10 (0 %)	1/10 (10 %)	ns
Contraction of identifiable mesh	−20.28 % ± 18.24	−61.18 % ± 17.25	0.0008
Biomechanics
All ewes
Comfort zone stiffness (N/mm)	0.68 ± 0.2	0.41 ± 0.46	ns
Comfort zone length (mm)	7.18 ± 2.00	8.52 ± 3.22	ns
Exclusion of outlier (n = 9)
Comfort zone stiffness (N/mm) (n = 9)	0.73 ± 0.29	0.27 ± 0.19	0.0101
Comfort zone length (mm) (n = 9)	7.30 ± 2.00	8.90 ± 3.17	ns

Biomechanical findings are displayed for all animals as well as results without the outlier, and contraction is displayed without those with unidentifiable or extruded material.