Prognostic factors that predict success in office endometrial ablation: a retrospective study

Smith, Paul P.; Karpate, Shilpaja; Clark, T. Justin

doi:10.1007/s10397-015-0921-5

Table 1 Factors assessed for prediction of further uterine surgical intervention after office endometrial ablation

From: Prognostic factors that predict success in office endometrial ablation: a retrospective study

Characteristic		No intervention (n = 340)	Further intervention (n = 51)	Univariable analysis		Multivariable analysis
Characteristic		No intervention (n = 340)	Further intervention (n = 51)	Odds ratio (95 % CI)	P ^*	Odds ratio (95 % CI)	P ^*
Age	>45	110 (33)	17 (35)	Reference
	40 to 45	135 (40)	12 (25)	0.59 (0.27 to 1.27)	0.2
	<40	96 (28)	20 (41)	1.36 (0.67 to 2.75)	0.5
BMI	<18.5	1 (0)	0 (0)	Not recordable
	18.5 to 25.0	95 (28)	7 (14)	Reference
	25.1 to 30.0	103 (30)	18 (37)	2.37 (0.95 to 5.93)	0.07
	>30.0	143 (42)	24 (49)	2.28 (0.94 to 4.570)	0.07
Previous caesarean		82 (24)	14 (29)	1.27 (0.65 to 2.47)	0.5
Endometrial ablation technique (bipolar radiofrequency vs thermal balloon)		189 (55)	29 (59)	1.17 (0.64 to 2.16)	0.6
Failed medical treatment		364 (92)	44 (90)	0.72 (0.26 to 1.98)	0.8
Phase of cycle	Secretory	110 (32)	17 (35)	Reference
	Proliferative	120 (35)	12 (25)	0.65 (0.30 to 1.42)	0.3
	Menses	33 (10)	6 (12)	1.18 (0.43 to 3.23)	0.8
	Progesterone effect	79 (23)	14 (29)	1.15 (0.53 to 2.46)	0.7
Uterine axis	Anteverted vs other	50 (15)	8 (16)	1.14 (0.51 to 2.57)	0.8
Abnormal hysteroscopy findings^a		57 (17)	7 (14)	0.83 (0.36 to 1.95)	0.7
Presence of fibroids^b		276 (81)	38 (78)	0.83 (0.40 to 1.70)	0.6
Duration of symptoms (months)		40.0 (43.4)^{c, d}	32.9 (32.0)^{c, e}	1.00 (0.99 to 1.00)	0.3
Uterine size >9 cm^f		65 (20)^g	18 (37)	2.28 (1.20 to 4.33)	0.01	3.13 (1.52 to 6.43)	0.002
Menstrual cycle irregular		137 (41)^h	17 (37)^j	0.84 (0.45 to 1.59)	0.6
Dysmenorrhea		208 (61)	41 (84)	3.30 (1.50 to 7.26)	0.003	4.82 (1.81 to 12.82)	0.002
Premenstrual syndrome		90 (26)	15 (31)	1.24 (0.64 to 2.37)	0.5
Antiplatelet drugs or anticoagulants		8 (2)	2 (4)	1.78 (0.37 to 8.62)	0.5

Data are n (%) unless otherwise specified
^* P = 1 significant figure
^aOf the 64 women who had abnormalities on hysteroscopy, 53 % had fibroid changes (either small submucous fibroids or slight distortions by intramural fibroids), 23 % had endometrial polyps, 14 % had congenital abnormalities (mildly arcuate) and 9 % had synechiae
^bFibroids of any location found on imaging, hysteroscopy or clinical examination
^cData are mean average (standard deviation)
^dData missing for 24 cases
^eData missing for 5 cases
^fMeasured on a uterine sound
^gData missing in 22 cases
^hData missing in 8 cases
ⁱData missing in 3 cases

Back to article page