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Table 3 Influence of each covariate on blood loss, operative time and complications

From: Surgical outcomes of laparoscopic hysterectomy with concomitant endometriosis without bowel or bladder dissection: a cohort analysis to define a case-mix variable

   Crude analysis Adjusted analysis
Blood loss (Geometric) mean + (G)SD§ or number (%) Percentage increase (95% CI) p value of univariate analysis Percentage increase (95% CI) Index patient* Data expressed in ml (95% CI) p value of multivariate analysis
Patient characteristics      
10LOG uterine weightɸ 153.6; 2.0    84.8 (74.5–95.4)   < .001
 BMI (increase/1 kg/m2) 28.5 ± 6.2    2.4 (1.8–3.0)   < .001
Previous procedures   -     
 Yes (versus no) 1213 (45.7)    13.1 (4.3–22.6)   < .001
Stage of endometriosis    < .001    < .001
 No endometriosis 67.3; 3.4 Reference   Reference 65.7 (57.2–75.6)  
 Stage I 71.4; 3.2 4.9 (−16.1–31.2) .68 7.6 (− 12.3–31.9) 70.7 (55.7–89.7) .48
 Stage II 79.0; 2.8 16.0 (− 7.3–44.9) .20 18.8 (− 3.2–45.6) 78.0 (61.4–99.2) .10
 Stage III 70.0; 3.6 27.9 (1–62.1) .04 34.0 (8.0–66.4) 88.1 (68.7–113.0) .01
 Stage IV 106.4; 2.9 98.8 (56.7–152.4) < .001 114.3 (72.1–166.7) 140.8 (109.4–180.9) < .001
Operative time Number (%) Percentage increase (95% CI) P-value of univariate analysis Percentage increase (95% CI) Index patient* Data expressed in min (95% CI) p value of multivariate analysis
Patient characteristics      
10LOG uterine weightɸ     20.0 (18.1–21.8)   < .001
 BMI (increase/1 kg/m2)     1.0 (0.8–1.2)   < .001
Previous procedures      
 Yes (versus no)     3.8 (1.5–6.1)   <.001
Stage of endometriosis    < 0.001    < .001
 No endometriosis 90.6; 1.5 Reference   Reference 92.0 (87.4–96.9)  
 Stage I 88.1; 1.5 − 4.4 (− 10.1–1.7) .16 − 3.3 (− 8.6–2.1) 88.9 (82.7–95.7) .23
 Stage II 81.9; 1.5 0.3 (− 5.7–6.7) .93 1.2 (− 4.3–6.9) 93.1 (86.5–100.3) .68
 Stage III 95.1; 1.5 15.3 (8.0–23.1) < .001 17.0 (10.3–24.0) 107.7 (99.8–116.2) < .001
 Stage IV 117.6; 1.6 47.6 (38.0–57.6) < .001 51.0 (42.3–60.3) 139.1 (128.8–150.1) < .001
Complications Number (%) Odds ratio (95% CI) p value of univariate analysis Odds ratio (95% CI) p value of multivariate analysis
Patient characteristics      
10LOG uterine weightɸ     0.69 (0.56–0.82)   < .001
 BMI (increase/1 kg/m2)     1.00 (0.98–1.03)   .935
Previous procedures      
 Yes (versus no)     1.17 (0.87–1.58)   .305
Stage of endometriosis    .72    .62
 No endometriosis 153 (6.8) Reference   Reference   
 Stage I (versus no) 5 (2.9) 1.27 (0.55–2.95) .57 1.27 (0.54–2.98)   .59
 Stage II 7 (4.0) 0.69 (0.33–1.43) .32 0.67 (0.32–1.36)   .26
 Stage III 4 (2.3) 1.23 (0.48–3.10)0.76 .67 1.16 (0.45–2.96)   .76
 Stage IV 6 (3.4) (0.34–1.65) .48 0.67 (0.30–1.50)   .34
  1. §Interpretation of the geometric standard deviation (GSD): 95% of the data are expected to lie in the range of GM/(GSD)2 to GM*(GSD)2
  2. *Index patient with BMI of 28.5, uterine weight of 161.3 g, and 50% previous procedures
  3. ɸThis means that for every tenfold increase in uterine weight, blood loss, and operative time increased by the stated percentages and odds of complication increased by the stated OR
  4. Statistics: linear mixed model (for outcome blood loss and operative time) and generalized linear mixed model (with logistic link function) (for outcome complications)
  5. 95% CI 95% confidence interval
  6. BMI body mass index, GM geometric mean, GSD geometric standard deviation