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Table 3 Influence of each covariate on blood loss, operative time and complications

From: Surgical outcomes of laparoscopic hysterectomy with concomitant endometriosis without bowel or bladder dissection: a cohort analysis to define a case-mix variable

  

Crude analysis

Adjusted analysis

Blood loss

(Geometric) mean + (G)SD§ or number (%)

Percentage increase (95% CI)

p value of univariate analysis

Percentage increase (95% CI)

Index patient*

Data expressed in ml (95% CI)

p value of multivariate analysis

Patient characteristics

 

–

    

 10LOG uterine weightɸ

153.6; 2.0

  

84.8 (74.5–95.4)

 

< .001

 BMI (increase/1 kg/m2)

28.5 ± 6.2

  

2.4 (1.8–3.0)

 

< .001

Previous procedures

 

-

    

 Yes (versus no)

1213 (45.7)

  

13.1 (4.3–22.6)

 

< .001

Stage of endometriosis

  

< .001

  

< .001

 No endometriosis

67.3; 3.4

Reference

 

Reference

65.7 (57.2–75.6)

 

 Stage I

71.4; 3.2

4.9 (−16.1–31.2)

.68

7.6 (− 12.3–31.9)

70.7 (55.7–89.7)

.48

 Stage II

79.0; 2.8

16.0 (− 7.3–44.9)

.20

18.8 (− 3.2–45.6)

78.0 (61.4–99.2)

.10

 Stage III

70.0; 3.6

27.9 (1–62.1)

.04

34.0 (8.0–66.4)

88.1 (68.7–113.0)

.01

 Stage IV

106.4; 2.9

98.8 (56.7–152.4)

< .001

114.3 (72.1–166.7)

140.8 (109.4–180.9)

< .001

Operative time

Number (%)

Percentage increase (95% CI)

P-value of univariate analysis

Percentage increase (95% CI)

Index patient*

Data expressed in min (95% CI)

p value of multivariate analysis

Patient characteristics

 

–

    

 10LOG uterine weightɸ

   

20.0 (18.1–21.8)

 

< .001

 BMI (increase/1 kg/m2)

   

1.0 (0.8–1.2)

 

< .001

Previous procedures

 

–

    

 Yes (versus no)

   

3.8 (1.5–6.1)

 

<.001

Stage of endometriosis

  

< 0.001

  

< .001

 No endometriosis

90.6; 1.5

Reference

 

Reference

92.0 (87.4–96.9)

 

 Stage I

88.1; 1.5

− 4.4 (− 10.1–1.7)

.16

− 3.3 (− 8.6–2.1)

88.9 (82.7–95.7)

.23

 Stage II

81.9; 1.5

0.3 (− 5.7–6.7)

.93

1.2 (− 4.3–6.9)

93.1 (86.5–100.3)

.68

 Stage III

95.1; 1.5

15.3 (8.0–23.1)

< .001

17.0 (10.3–24.0)

107.7 (99.8–116.2)

< .001

 Stage IV

117.6; 1.6

47.6 (38.0–57.6)

< .001

51.0 (42.3–60.3)

139.1 (128.8–150.1)

< .001

Complications

Number (%)

Odds ratio (95% CI)

p value of univariate analysis

Odds ratio (95% CI)

–

p value of multivariate analysis

Patient characteristics

 

–

    

 10LOG uterine weightɸ

   

0.69 (0.56–0.82)

 

< .001

 BMI (increase/1 kg/m2)

   

1.00 (0.98–1.03)

 

.935

Previous procedures

 

–

    

 Yes (versus no)

   

1.17 (0.87–1.58)

 

.305

Stage of endometriosis

  

.72

  

.62

 No endometriosis

153 (6.8)

Reference

 

Reference

  

 Stage I (versus no)

5 (2.9)

1.27 (0.55–2.95)

.57

1.27 (0.54–2.98)

 

.59

 Stage II

7 (4.0)

0.69 (0.33–1.43)

.32

0.67 (0.32–1.36)

 

.26

 Stage III

4 (2.3)

1.23 (0.48–3.10)0.76

.67

1.16 (0.45–2.96)

 

.76

 Stage IV

6 (3.4)

(0.34–1.65)

.48

0.67 (0.30–1.50)

 

.34

  1. §Interpretation of the geometric standard deviation (GSD): 95% of the data are expected to lie in the range of GM/(GSD)2 to GM*(GSD)2
  2. *Index patient with BMI of 28.5, uterine weight of 161.3 g, and 50% previous procedures
  3. ɸThis means that for every tenfold increase in uterine weight, blood loss, and operative time increased by the stated percentages and odds of complication increased by the stated OR
  4. Statistics: linear mixed model (for outcome blood loss and operative time) and generalized linear mixed model (with logistic link function) (for outcome complications)
  5. 95% CI 95% confidence interval
  6. BMI body mass index, GM geometric mean, GSD geometric standard deviation
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