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Table 5 Primary surgical treatment of interstitial pregnancy

From: Elective uterine artery embolization prior to laparoscopic resection of interstitial pregnancy: two cases and literature review

Author N Initial β-hCG Surgical treatment Duration Rupture Hospital stay Negative β-hCG Complications Success
Moon et al. [38] 3 1320–24,700 Laparoscopic CS° 52 No N/A N/A 3/3
  18 28.5–305,100 Laparoscopic CS°° U:28; R:82 3/18 N/A N/A 17/18
  3 4469–13,000 Laparoscopic CS°°° 35 No N/A N/A 3/3
Tulandi et al. [39] 13 11,471 Laparotomic CR N/A 9/13 N/A N/A Transfusion 7/13 13/13
  8 2087 Laparoscopic CR N/A 5/11 N/A N/A Transfusion 2/11 7/8
  3 2087 Laparoscopic CS N/A 5/11 N/A N/A Transfusion 2/11 3/3
MacRae et al. [40] 3 3150–38,000 Laparoscopic CS N/A 1/3 2 N/A 3/3
  8 0–21,352 Laparoscopic CR N/A 3/8 2 N/A Conversion: 1/8 7/8
Ng et al. [41] 53 N/A Laparoscopic CS if IP 1–2 cm° Laparoscopic CR if IP ≥ 3 cm° 67 (mean) 8/53 2 3 Conversion: 1/53 Transfusion: 8/53 44/53
Moon et al. [14] 20 177–39,508 Laparoscopic CS° N/A 2/20 N/A N/A 19/20
Hwang et al. [42] 54 12,741 Laparotomic CR 71 19/54 6 N/A Transfusion 25/54 54/54
  34 12,905 Laparoscopic CR 81 8/34 5 N/A Transfusion 13/34 34/34
Cai et al. [43] 15 N/A Laparoscopic CS° 30–80 N/A 2–5 2–5 15/15
  7 3000–32,000 TE, LG and HG 45–90 No N/A 2–5 Perforation: 2/7 5/7
Zuo et al. [44] 16 14,696 Laparoscopic CR 25–120 No 3–4 N/A Rupture: 1/16 16/16
Ahn et al. [45] 6 17,797–69,303 TE, UG N/A N/A 2–8 N/A 5/6
  9 20,319–50,271 Laparoscopic CR N/A N/A 4–7 N/A Transfusion: 1/9 9/9
Douysset et al. [46] 13 369–45,780 Laparoscopic CR N/A 9/18 5 N/A Transfusion: 4/18 11/13
  5 369–45,780 Laparoscopic CS N/A 9/18 5 N/A Transfusion: 4/18 4/5
Watanabe et al. [47] 12 998–55,820 Laparoscopic CS° 61–160 2/12 N/A N/A 12/12
  1 69 Laparoscopic CS° N/A Yes N/A N/A 1/1
Kim et al. [11] 13* N/A Laparoscopic CR 40–145 2/13 2–7 N/A Rupture 1/11 Transfusion: 2/13 Miscarriage: 1/13 13/13
Nikodijevic et al. [48] 13 16,687 Laparoscopic CR N/A N/A N/A 4–8 Conversion: 5/13 Transfusion: 4/13 13/13
Nirgianakis et al. [49] 10 27,634 Laparoscopic CR~ 115 N/A 3 N/A Transfusion: 3/10 10/10
Wang et al. [50] 38 25,150 Laparoscopic CS° 71 11/38 3 N/A 35/38
Lee et al. [51] 53 575–64,831 Laparoscopic CR 77 N/A N/A N/A 49/53
  22 1454–62,422 Laparoscopic CS, ° 59 N/A N/A N/A 21/22
  1. N number of cases, β-hCG mIU/ml, CR cornual resection, CS cornuostomy, IP interstitial pregnancy, TE transcervical evacuation, HG under hysteroscopic guidance, LG under laparoscopic guidance, R ruptured, UR unruptured, duration minutes, hospital stay days, negative β-hCG weeks
  2. Hemostatic technique: °vasopressin, °°endoloop, °°°encircling suture, *heterotopic pregnancy