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Table 8 Secondary/tertiary systemic/local medical treatment of interstitial treatment

From: Elective uterine artery embolization prior to laparoscopic resection of interstitial pregnancy: two cases and literature review

Author

N

Initial

β-hCG

Initial treatment

Medical treatment

Hospital stay

Negative β-hCG

Complications

Success

Fisch et al. [56]

1

102,000

SMTX

MTX 50 mg intrasaccular

11

7

–

1/1

Moon et al. [38]

1

47,200

Laparoscopic CS

MTX

N/A

N/A

N/A

1/1

Tulandi et al. [39]

1

2086

Laparoscopic CR

MTX

N/A

N/A

N/A

1/1

Takeda et al. [94]

1

16,100

Laparoscopic CS

MTX

30

N/A

N/A

1/1

Araujo et al. [64]

1

4815

SMTX

LMTX (50 mg), UG

N/A

N/A

–

1/1

Fujioka et al. [65]

1

11,430

SMTX

Dactinomycin 12 μg/kg IV

N/A

N/A

–

1/1

MacRae et al. [40]

1

7237

Laparoscopic CR

SMTX

N/A

N/A

N/A

1/1

Ng et al. [41]

9

N/A

Laparoscopy

SMTX

N/A

N/A

N/A

9/9

Sahoo et al. [95]

1

12,000

Laparoscopy

SMTX

N/A

N/A

–

1/1

Moon et al. [14]

1

9836

Laparoscopic CS

SMTX

N/A

N/A

N/A

1/1

Kato et al. [68]

1

90,000

SMTX

LMTX (25 mg)

N/A

6

–

1/1

Surbone et al. [74]

1

N/A

LMTX

SMTX

N/A

N/A

N/A

0/1

Douysset et al. [46]

2

N/A

Laparoscopic CR

MTX

N/A

N/A

N/A

2/2

 

1

N/A

Laparoscopic CS

MTX

N/A

N/A

N/A

1/1

Poon et al. [96]

2

3658–89,968

Expectant

LMTX

N/A

N/A

N/A

2/2

Wang et al. [50]

1

N/A

Laparoscopic CS

MTX 20 mg IM for 5 days

N/A

4

–

1/1

Lee et al. [51]

5

N/A

Laparoscopy

MTX multiple dose regimen

N/A

N/A

–

5/5

  1. N number of cases, β-hCG mIU/ml, (S/L)MTX (systemic/local) methotrexate, CR cornual resection, CS cornuostomy, IM intramuscular, IV intravenous, UG under ultrasound guidance, hospital stay days, negative β-hCG weeks
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