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Table 4 Combined data from current studies on medical management of interstitial ectopic pregnancy

From: The diagnosis and management of interstitial ectopic pregnancies: a review

Study Number of patients in total Number of patients successfully managed (local and systemic MTX) Number of patients managed with systemic MTX Number of patients successfully managed (systemic MTX) Number of patients managed with local MTX Number of patients successfully managed (local MTX)
Hafner et al. 1999 [16] 10 9 5 4 5 5
Jermy et al. 2004 [20] 18 14 18 14 N/A N/A
Tulandi et al 2004 [44] 8 5 N/A N/A N/A N/A
Cassik et al. 2005 [8] 28 24 5 4 23 21
Tang et al. 2006 [42] 11 10 11 10 N/A N/A
Surbone et al. 2013 [38] 9 8 3 2 6 6
Hiesch et al. 2014 [17] 17 12 17 12 N/A N/A
Framarino et al. 2014 [15] 14 14 N/A N/A 14 14
Tanaka et al. 2015 [40] 33 31 33 31 N/A N/A
Total 148 127 92 77 48 46
Success rate (95%CI)   85.81% (84.17–87.45)   79.98% (72.68–87.29)   97.83% (93.56–100)
  1. N/A implies that the particular study did not consider patients managed with that treatment