The diagnosis and management of interstitial ectopic pregnancies: a review

Table 4 Combined data from current studies on medical management of interstitial ectopic pregnancy

Study	Number of patients in total	Number of patients successfully managed (local and systemic MTX)	Number of patients managed with systemic MTX	Number of patients successfully managed (systemic MTX)	Number of patients managed with local MTX	Number of patients successfully managed (local MTX)
Hafner et al. 1999 [16]	10	9	5	4	5	5
Jermy et al. 2004 [20]	18	14	18	14	N/A	N/A
Tulandi et al 2004 [44]	8	5	N/A	N/A	N/A	N/A
Cassik et al. 2005 [8]	28	24	5	4	23	21
Tang et al. 2006 [42]	11	10	11	10	N/A	N/A
Surbone et al. 2013 [38]	9	8	3	2	6	6
Hiesch et al. 2014 [17]	17	12	17	12	N/A	N/A
Framarino et al. 2014 [15]	14	14	N/A	N/A	14	14
Tanaka et al. 2015 [40]	33	31	33	31	N/A	N/A
Total	148	127	92	77	48	46
Success rate (95%CI)		85.81% (84.17–87.45)		79.98% (72.68–87.29)		97.83% (93.56–100)

N/A implies that the particular study did not consider patients managed with that treatment