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Table 2 Primary systemic MTX treatment of interstitial pregnancy

From: Elective uterine artery embolization prior to laparoscopic resection of interstitial pregnancy: two cases and literature review

Author

N

Initial β-hCG

Systemic MTX treatment

Hospital stay

Negative β-hCG

Success

Jermy et al. [24]

17

32–31,381

50 mg/m2 IM

0–40

3–13

16/17

Hiersch et al. [25]

14

15,764

1 mg/kg/d IM on day 1, 3, 5, 7

N/A

N/A

9/14

 

3

< 2500

50 mg/m2 IM

1

N/A

3/3

Tanaka et al. [26]

33

230–106,634

100 mg IV + 200 mg IV

1–4

3–19

31/33

Kim et al. [12]

5

375–102,970

1 mg/kg/d IM on day 1, 3, 5, 7

N/A

N/A

14/30

 

24

 

50 mg/m2 IM

N/A

N/A

 
 

1

 

100 mg IV in bolus followed by 200 mg IV

N/A

N/A

 
  1. N number of cases, β-hCG mIU/ml, MTX methotrexate, IM intramuscular, IV intravenous, hospital stay days, negative β-hCG weeks